You can mix it, and if you aren't doing any "performance' driving, it won't make a major difference. However, if you want to get out on the edge a little at times, you are going to face the issue of unequal expansion rates in your tires. A tire with mostly nitrogen will expand at one rate, the tire with a greater mix of ambient air will expand at a different rate (as they heat up). This effects the shape of the contact patch on your tire. Four tires with different mixes of nitrogen and air will take four different shapes as they heat up. No big deal on a burger run to White Castle. Could be a very big deal if you decide to get a little sporty on your trip home.
Almost forgot. Don't know how nitrogen does in terms of leakdown rates. Race tires are so leaky from day one that we are constanly adding nitrogen, sometimes as much as three or four times a day.
Best bet is either be a nitrogen guy or an air guy.