I'll take that one. Unless the next generation Viper has a dramatic reduction in power, or Government Motors manages to get ZR-1 power out of the base Vette, that's not even a possibility. Let's try a more realistic comparison: 2006 Gen III Viper Coupe, vs. 2006 Z-06 Vette (I owned both and drove both so I can compare the two with the same driver; the horsepower is close to even, Vette has T/C and ESC, and a better stock rear gear ratio; sticker differential was about 20k.) I think that would meet your parameters; if T/C and ESC really make for better performance, the Vette should be the clear winner, on paper.
Now, here's what I found in the real world: On the street, one performs about as well as the other. Viper steering is a bit more accurate, ride (on runflats) is slightly harsher in the Viper, Viper seats much more supportive than Vette seats, Vette ESC is not intrusive. Overall, street performance is a virtual tie; Viper gets far more looks. Drag racing, the Vette is marginally easier to launch, but not by much; 0-60 and 1/4 mile times are close enough to make it a driver's race with average drivers in each. Overall slight advantage Vette (borne out by most subsequent experience among a variety of drivers). Autocross, Viper's superior braking begins to tell; without practice, it's easier to get the Vette off corners (in recommended mode which is T/C off, ESC partially engaged). With practice, however, it's easier to steer the rear in the Viper, and eventually my times in the Viper are consistently better than in the Vette. Both cars can and will spin with clumsy/abrupt throttle/steering inputs. Advantage, Viper. Road course, here is where the Viper belongs. Sticks like glue in corners; some push, mostly taken car of with air pressure adjustment in the fronts. Handling is stable and predictable; can out brake the Vette on corner entry every time. Vette feels better coming off corners at first, but when pushed a bit more, feels nervous and a little tail happy, with or without ESC. Overall feel of the Vette is less predictable, and how the heck did Magnussen drive the Ring on these tires? Even warmed up, they feel greasy. At a smooth 85-90% (my personal limit), Viper inspires confidence....Vette inspires me to leave ESC turned on, in case it gets too squirrelly. Bottom line: the vette spends most of its time with me on the street (it IS a good daily driver). Viper ends up being my track day and autocross car. Side note: I see a distressing number of crashes and near-crashes reported on the Vette forums, in which the ESC apparently failed to catch the car after sudden inputs; this squares with my own informal parking lot tests, in which I find it quite possible to spin the rear out with abrupt heavy throttle; sudden demand on a 500hp engine is more than the computer can handle, it seems.
So for me, the Viper is the better answer. I have not bought another Vette, but I sure did buy a Gen IV Viper, which is, in my limited experience so far, a quantum leap forward from both the Gen III Snake and the Z-06. Ride and handling are better (at least at normal speeds); it feels utterly composed, handling the back roads out my way like a fine road car; I can't wait for warmer weather to see what it can do on the track. Do I feel safe in it, even without ESC? Absolutely! Provided I do my part, I know exactly what the Viper will and won't do. Worth the money? In my opinion, definitely!
You did ask......