Dan, why do you say the AEM can't work on a Gen IV (assuming someone had an AEM box)? Could it not be run along with the factory ECU? Have you tried it?
-For starters, it would be an installation nightmare so far as AEM goes, as it is a JTEC based controller, and the VENOM controller is not JTEC. The VENOM has a completely different layout. It would end up being as much or more work than a Standalone installation.
-The AEM does not have enough ignition drivers, so you would be in the same boat as trying to get a Gen-4 to run on an SQ6 controller.
-I don't believe the AEM can even read the Gen-4 Crank/Cam trigger configuration correctly, it is much more complex than earlier cars.
-Camshaft control in AEMPro is very limited in capability compared to Pectel/Motec, and does not even appear to be able to correctly run the Gen-4 Camshaft. It is primarily set up for VTEC [On/Off] Cam control, not a continuously variable camshaft.
-The Venom Controller defaults to Limp Mode very easily, so you can bet your bottom dollar that if you try to leave any controls to the VENOM that have to do with running the engine, they are going to be a fight to keep running correctly.
No, I have not tried it, and as far as I know, no one else has either. There are far too many apparent "issues" to overcome to justify the potential waste of time that is more than likely going to result, especially when factoring in that it is an obsolete design, and there are better options available that everyone knows WILL work.